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Thank you for helping ELSO disseminate information by entering your experience in the ELSO Registry as soon as ECMO is implanted - before the run is complete. Instructions for entering data in the Registry and COVID-19 addendum can be found on the Data Definitions page.



We recognize you cannot complete and submit the entire ELSO Registry case report form prior to completion of the ECMO run and discharge from the hospital, but we would still like to have the data you know now.



To address concerns about incomplete data we report three nested data sets to accommodate the fact that different patients will be at different stages of care (and thus have more or less incomplete data). Also when considering the data please understand that the data displayed is a real-time data stream and subject to change as more patient information is accrued and as centers update the ELSO Registry Case Report Form and the ELSO COVID-19 addendum.

COVID-19 Cases on ECMO in the ELSO Registry

Total COVID-19 Cases COVID-19
Confirmed Cases
17,752
Total counts of COVID-19 confirmed patients.

COVID-19 ECMO counts by ELSO Chapter

Still on ECMO Still Hospitalized at ELSO Center Total (n)
All ELSO 362 691 18,015
          North America 87 167 11,462
          Europe 136 192 3,528
          Asia Pacific 39 93 568
          Latin America 77 192 1,271
          SWAAC 23 47 1,185
Reports counts of ECMO-supported suspected or confirmed COVID-19 cases by ELSO Chapter

Filters affect the data shown in the tables below:

Year To Date

Region

Patient Age


Patients who initiated ECMO at
least 90 days ago
COVID-19
Confirmed
16,209
COVID-19
In-hospital Mortality
48%

Outcomes

Pre-ECMO Patient Factors

Patient-level summaries of COVID ECMO runs. All categorical variables are given as 'percentage (count)'
Total ARDS Cohort
Number cases 16209 11983
Age(years)
Median(IQR) 47(37,56) 48(38,56)
# observed 16209 11983
BMI, kg/m2
Median(IQR) 32(27,37) 32(28,38)
# observed 15024 11076
Sex
Male 68%(11053) 70%(8329)
Female 32%(5152) 30%(3651)
# observed 16205 11980
Race/Ethnicity
Black 11%(1707) 10%(1207)
White (Non-Hispanic) 44%(7134) 43%(5207)
Asian 9%(1407) 8%(976)
Mid East, N African 4%(701) 5%(575)
Other 3%(465) 3%(344)
Unknown 5%(792) 5%(610)
Multiple 5%(840) 6%(699)
Hispanic 20%(3163) 20%(2365)
# observed 16209 11983
Pre-ECMO Comorbidities
No comorbidity 26%(4201) 24%(2933)
Cancer 2%(304) 2%(208)
Pregnancy 4%(645) 4%(490)
Immunocompromised 5%(809) 5%(600)
Diabetes 23%(3768) 24%(2894)
Pre-existing heart disease 4%(695) 3%(340)
Pre-existing lung disease 4%(645) 4%(476)
Pre-existing renal insuff. 3%(505) 3%(346)
Frailty 1%(145) 1%(82)
Asthma 10%(1628) 10%(1242)
BMI $> 30 \mathrm{kg}/\mathrm{m}^2$ 48%(7856) 51%(6126)
Hypertension 31%(4966) 32%(3817)
# observed 16209 11983
Acute illness
ARDS 78%(12706) 100%(11983)
Acute heart failure 9%(1412) 5%(606)
Myocarditis 2%(397) 1%(66)
Acute kidney injury 26%(4246) 27%(3204)
# observed 16209 11983
Pre-ECMO Cardiac Arrest
Yes 7%(1087) 3%(360)
No 93%(14966) 97%(11500)
# observed 16053 11860
Pre-ECMO Co-Infection
No Co-infection 49%(7934) 46%(5533)
Bacterial pneumonia 44%(7105) 47%(5678)
Co-viral infection 9%(1520) 9%(1070)
Blood stream infection 18%(2898) 19%(2278)
Urinary tract infection 7%(1211) 8%(1006)
# observed 16207 11981

Pre-ECMO Interventions

Support and therapies. All categorical variables are given as 'percentage (count)'
PreECLS PreECLS
Number cases 16209 11983
Noninvasive ventilation
Noninvasive ventilation prior to intubation 75%(12221) 80%(9553)
BiPAP 37%(6056) 41%(4876)
CPAP 12%(2023) 12%(1436)
HFNC 51%(8211) 55%(6565)
# observed 16209 11983
Pre-ECLS intubation (days)
Median(IQR) 2.8(0.7,5.9) 3.2(1.0,6.2)
# observed 13422 9983
Ventilator mode
Conventional 96%(13099) 97%(10028)
# observed 13694 10351
PEEP, cm H2O
Median(IQR) 14.0(10.0,16.0) 14.0(10.0,16.0)
# observed 12152 9342
PIP, cm H2O
Median(IQR) 33.0(29.0,38.0) 34.0(30.0,38.0)
# observed 9728 7413
FiO2
Median(IQR) 1.00(0.95,1.00) 1.00(1.00,1.00)
# observed 12051 9123
PaO2/FiO2
Median(IQR) 70(57,92) 70(57,89)
# observed 11779 8926
PCO2
Median(IQR) 60(49,74) 61(51,75)
# observed 12534 9446
Pre-ECMO Support
Prone positioning 51%(8178) 55%(6610)
# observed 16128 11929
Neuromuscular blockers 67%(10755) 71%(8519)
# observed 16131 11928
Inhaled pulmonary vasodilators 28%(4454) 30%(3616)
# observed 16128 11929
Any vasoactive support 57%(9244) 56%(6655)
# observed 16127 11923
Norepinephrine 51%(8174) 51%(6052)
# observed 16127 11923
Therapies, Immunomodulators
Any therapy 86%(14011) 90%(10762)
Glucocorticoids 78%(12581) 81%(9719)
IVIG 3%(454) 2%(239)
Anti-cytokine 21%(3445) 24%(2829)
Lopinavir/Ritonavir 2%(280) 2%(229)
JAK inhibition 4%(574) 4%(487)
Chloroquine/hydroxychloroquine 6%(1025) 7%(833)
Remdesivir 48%(7743) 51%(6136)
# observed 16209 11983
Support type
Respiratory 92%(14936) 100%(11956)
Cardiac 6%(970) 0%(12)
ECPR 2%(303) 0%(15)
# observed 16209 11983

Patient Status & Complications

Outcomes
Total ARDS Cohort
Last known patient status
Discharged alive to home or acute rehabilitation 26%(4287) 26%(3072)
Discharged alive to long-term acute care or unspecified location 12%(1875) 13%(1508)
Discharged to another hospital 12%(1895) 11%(1323)
Remain in the hospital (discharged from ICU) 0%(7) 0%(4)
Remain in the ICU 0%(48) 0%(34)
In-hospital death 50%(8097) 50%(6042)
Tracheostomy 46%(6730) 50%(5478)
# observed 14694 10867
Select complications
Seizures 1%(124) 1%(88)
# observed 16147 11930
CNS infarction by US/CT/MRI 2%(271) 1%(161)
# observed 16147 11930
CNS hemorrhage by US/CT/MRI 6%(1017) 7%(797)
# observed 16147 11930
Hemolysis 7%(1172) 8%(901)
# observed 16147 11930
Oxygenator failure 21%(3343) 23%(2768)
# observed 16147 11930
Pump failure 2%(330) 2%(262)
# observed 16147 11930
Circuit change 11%(1746) 12%(1396)
# observed 16147 11930
Thrombosis/Clots in circuit component 3%(534) 4%(427)
# observed 16147 11930
Discharge location
Home 31%(2530) 31%(1809)
Transfer to LTAC or Rehab
Transfer to another hospital 24%(1895) 22%(1323)
Other/Unknown 6%(453) 5%(316)
*N/A - Data elements with n<5 are not displayed.